Imagine Life

Without Pain

Non-Surgical Orthopedics

Advanced Regenerative Medicine in Pittsburgh | Non-Surgical Solutions for Joint & Sports Injuries

Regenexx Pittsburgh is your premier destination for pioneering non-surgical regenerative medicine treatments. Our state-of-the-art approaches to joint and sports injuries are tailored to reduce pain and improve function without the need for invasive surgeries, right here in Pittsburgh.

More than 132,400 highly specific image-guided Regenexx® Procedures have been performed since Regenexx pioneered the use of orthopedic bone marrow concentrate to treat common orthopedic problems in 2005.
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The published research on Regenexx procedures accounts for approx. 44% of the world’s research on the use of bone marrow concentrate for orthopedic conditions (cumulative n of patients published & treated with bone marrow concentrate as of 1/1/2019)
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Transform Your Life with Regenexx - Leading Regenerative Orthopedics

At Regenexx Pittsburgh, we believe that quality of life shouldn’t be compromised by chronic pain. Our leading-edge regenerative orthopedics solutions offer a unique path to improved function, without the need for surgery.

Specializing in techniques such as bone marrow concentrate using your body’s own stem cells (commonly referred to as “stem cell therapy”) and platelet-rich plasma (PRP) treatments, we provide personalized care designed to target root causes of joint pain.

Every patient’s pain is unique, and so are our treatments. At Regenexx Pittsburgh, we meticulously craft customized regenerative medicine protocols based on your specific condition, activity level, and health goals.

Whether you’re an athlete looking to return to your sport or someone struggling with daily activities due to chronic pain, our targeted therapies are designed to help you regain function and improve quality of life without surgery.

Choosing the right clinic for your regenerative medicine needs is crucial. Regenexx Pittsburgh stands out as a leader in non-surgical orthopedic treatments, thanks to our:

Experience Top Non-Surgical Orthopedic Care in Pittsburgh

State-of-the-Art Joint Pain Reduction Near You

Pittsburgh's Premier Regenerative Sports Medicine Services

Athletes and active individuals in Pittsburgh no longer need to choose between enduring pain or facing surgery. Regenexx Pittsburgh specializes in regenerative sports medicine, offering treatments that are specifically designed to aid your body’s recovery from sports-related injuries.

Our services, including PRP therapy and bone marrow concentrate, are viable alternatives to surgery for patients with ligament tears, tendon damage, and joint instability.

By focusing on enhancing your body’s natural healing processes, we help athletes of all levels return to their peak performance without lengthy downtimes.

Where are you Experiencing Pain?

Meet Our Regenexx Pittsburgh Board Certified Physicians

Dr. Lieber, JD

Dr. Paul Lieber, MD - Expert in Regenerative Treatments

Marc Adelsheimer, MD

Dr. Marc Adelsheimer, MD - Your Regenerative Medicine Specialist

Jesse A. Sally, DO

Dr. Jesse A. Sally, DO - Dedicated to Non-Surgical Recovery

Ask Our Doctors How You Can Get Back to the Things You Love, Faster and Without Surgery

Regenexx Physicians represent a very selective, highly-skilled, interventional orthopedics network that is 100% focused on joint, tendon, ligament, spine, and bone conditions. All Regenexx physicians are musculoskeletal experts with extensive training and experience in the diagnosis and treatment of musculoskeletal conditions, as well as complex, image-guided injections of your body’s own healing agents to treat orthopedic issues.

I had prp injected into my L1, L2 facet joints and surrounding ligaments and muscles. Dr. Sally was very truthful, professional, skilled and knowledgeable. I would highly recommend him, Regenexx and the prp treatment I received.read more
Justin Craig
Justin Craig
23:30 23 Jan 24
I want to share my experience with Regenexx. I had my doubts when I first learned of this science. Since then I have had both knees treated with stem cell and PRP treatments. I have seen remarkable progress over the past few months. The entire experience has been positive and I have been treated by doctors and staff with professionalism. I would recommend this process to anyone struggling with the discomfort of osteoarthritis in the kneesread more
Joe Schlimm
Joe Schlimm
14:50 23 Jun 23
I can’t thank Dr Lieber enough. I went to him with spinal stenosis and two herniated disc in my lower back. Dr Lieber answered all my questions and we decided to the PRP treatment. I am now without pain and can enjoy life. I would highly recommend Dr Lieber to anyone.read more
Brenda Hlavsa
Brenda Hlavsa
16:11 14 Jun 23
Dr. Sally and his staff could not have been more professional, caring or effective! I had a great experience with the PRP treatment for my shoulder from Dr. Sally. I can't recommend the nitrous oxide enough! (I also recommend using stainless steal on the site after the treatment to reduce the pain. I know this is a very unusual idea but it works like a charm for bumps, bruises and even dental visits!)I am 4 months out from the procedure and am very confident that I will be swinging a tennis racket by summer!read more
Mary Smith
Mary Smith
16:16 17 May 23
Dr Sally always answers my questions, there's a bad review about only getting relief from an injection for a week. I'm in the same boat and insurance only covers it if you get certain % of relief. I had sacroiliac joint injection and got a weeks relief and slept better than I had in ages, but it was short lasting. But at least I know where the pains coming from now.Also he does great with my Botox injections and my trigger point injections, he is even a good sport a out me being a huge injection baby.read more
MacKenzie L
MacKenzie L
12:16 02 May 23
The doctor was very honest about my partner not qualifying for the procedures, which was good in a way. But they had us waiting in a room for 30m for someone to come check us out, which never happened. We ended up getting out of the room and finding a bunch of nurses talking between themselves and unaware of the situation.read more
Clara Bueno
Clara Bueno
19:01 07 Feb 23
Regenexx Pgh --- Look no further if you need PRP therapy! Dr. Sally performed platelet rich plasma (PRP) therapy on my left posterior tibial tendon. After the procedure I experienced some swelling and very little pain. The pain and swelling were so minimal that I did not take any Tylenol!Background:1. I am a 59 year old female who is fairly active.2. I had chronic posterior tibial tendinitis (5 years).3. I received steroid shots 5 years ago, physical therapy (dry needling, cold laser, etc.), orthotics, etc.4. My symptoms came back about a year ago because I did not realize the tendon did not fully heal. So, I had X-rays (ankle & feet) and a MRI that revealed damage to the tendon. I got another custom orthotic, but wanted to SOLVE the problem! (if possible) Plus, I didn't want to tear the tendon completely and have surgery!5. I started researching possible solutions. I spent numerous hours researching PRP therapy & other modalities. The data is all of the place (for PRP) because there is no "standard" procedure (in my opinion). After sifting through the data, I landed on the Regenexx procedure for many reasons. (I don't want to list them otherwise this review will be even longer! Go to the Regenexx site!)6. My sister lives in Pittsburgh and had several friends experience positive results with Regenexx Pittsburgh. So, I signed up for one of their webinars, spoke with their staff and made a telehealth visit with Dr. Sally. (I live in South Georgia.) Dr. Sally was very professional and answered all of my questions.7. Regenexx Pgh - They have this procedure fine tuned! From the moment I inquired about information, EVERY person responded in a timely, friendly, and professional manner. They answered every question and provided me with everything I needed to make my decision. I knew EXACTLY what it would cost, what to expect, success rate, etc. They were in constant contact with me.8. They provide you with an extensive list of preparations and videos so you can have the best possible outcome.Outcome:1. On the day of the procedure, I had my blood drawn (great phlebotomist/nurse) and a few hours later I had the procedure. Dr. Sally and his nurse were excellent. Dr. Sally was very patient with me because I asked a lot of questions and he explained everything so well.2. I cannot say enough about the Regenexx team in Pittsburgh. From the office staff, phlebotomist, nurses, consultants, & of course, Dr. Sally, this has been an exceptional experience.3. They use image-guided injections so they can pinpoint the location of the problem. I feel this is SO important for a successful outcome.4. I am in week 6 after the procedure and am probably at the 85% mark. I go to physical therapy twice a week and will continue with this care plan until my tendon is healed. (I do my physical therapy exercises at home too, wear a custom orthotic when needed, and eat a healthy diet. I am motivated!) I felt so good after the procedure, that it has been challenging for me to not become really active right away! It takes patience!5. I will have another follow up appointment with Dr. Sally in a few months.Bottom line: Regenexx Pittsburgh is where you want to go for a successful PRP procedure! I wish insurance providers would cover the cost of the procedure, because in my opinion, it is better to solve the problem early before the damage is too great and the patient needs surgery. Surgery is VERY expensive compared to PRP!read more
Lori Stauffer
Lori Stauffer
18:28 07 Jan 23
The staff was professional and friendly! The doctor explained everything he would be doing and how it worked. My knee feels 100% better then before the procedure and probably the best it's felt in 20+ years. I would definitely recommend this procedure and would do it again if I need another joint done in the future.Thank you Dr. Lieber and your staff!!!read more
Joseph Kirven
Joseph Kirven
16:33 06 Jan 23
I have struggled with low back pain due to a disc herniation for over 10 years. The orthopedics I went to continued to recommend steroid injections for the pain and said I would need to continue getting them every couple of years for the rest of my life! Being in my early 30's, I didn't want to accept that for myself, so I looked for alternatives and found Regenexx. I'm so beyond pleased with the results! It made the biggest difference in jump starting my recovery. I was able to not only do the physical therapy exercises suggested in the past, but I built up strength in my back and returned to weightlifting I haven't been able to perform in years. Prior to my Regenexx procedure, I was extremely limited in the types of exercises I was doing (no squatting or bending over), had trouble sleeping and performing simple tasks around the house. I'm now about 6 months post procedure and I have no pain while sleeping and no restrictions in daily tasks. I can do any type of exercise I want and I'm building strength to prevent injury in the future. I recommend Dr. Sally and the whole Regenexx team to anyone who is looking for a long term solution to their pain. I can't put into words how happy I am that I made the decision to try Regenexx!read more
Stephanie Wilson
Stephanie Wilson
17:08 05 Dec 22
Very friendly and helpful staff . Would recommend to anyone looking for a stem cell treatment.
Brenda Wood
Brenda Wood
19:16 21 Oct 22
6 weeks ago I had PRP in both my knees and right thumb joint at Regenexx, Pittsburgh. I also had stem cells, my own, injected into my right knee which has been bone on bone for many, many years. It was a decision I had done much research on and spent many many hours reviewing information from other sites, not related to Regenexx as I did not want to be influenced by their information until I had researched and visited the others that I had considered. I truly was saving the best for last!!!. I had requested information from Regenexx approximately 6 years ago.My story is long and filled with much emotion. I will be brief---after the first of the three procedures, I felt no pain in the three sites that were cared for. It has been 6 weeks since all of this and I am still doing physical therapy and water therapy. I would do this again in a minute. My Dr was always professional, caring, and usually answered my questions before I ask as he was amazingly thorough. My calls and concerns were always answered immediately. I felt that my care was their ultimate concern. I looked at other places.... and none measured up to Regenexx. I would truly suggest each person considering this procedure do your own research, take your time, and visit Regenexx to compare any others that you may have considered. It's your health, its your life, its life changing. My deepest thanks to Dr Sally and his amazing staff.read more
Denise Defazio
Denise Defazio
00:25 14 Sep 22
I am from Upstate NY. A friend had the knee stem cell procedure at Regenexx by Dr Sally. It turned out well, so I contacted Regenexx and was approved for a knee procedure also. This was last year.The staff were very kind. Dr Sally answered all my questions with great patience.The procedure went well. My kneeIs 95% better!The healing process took longer than I anticipated, and the swelling hindered me from being able to get around for a few weeks, but I came to realize people heal at different rates.I had a torn meniscus, with arthritis. Was using crutches before going there. I was in bad shape beforehand. So, it took longer to heal, I believe.It was worth the effort of going to PT and doing exercise at home to help my body recover. Going up and down stairs is much better now!I am in the process of deciding to have my other knee done, because of the arthritis.It was worth the 5 hour trip to travel there.I am comfortable with the Dr's ability to repair my knee!A hearty thank you to all involved in my care!read more
Robin M
Robin M
17:11 17 Aug 22
Dr Lieber is great. Highly recommend.
Elliott Baxter
Elliott Baxter
15:15 12 Jul 22
They are the best!
Deborah Fajbik
Deborah Fajbik
04:56 04 Jun 22
Really happy with the stem cell procedure. Staff spends plenty of time with you to look at options and know what the treatment and follow up will look like. I have already referred others to Dr. Leiber and this office.read more
Lindsay Bacchi
Lindsay Bacchi
02:30 19 Apr 22
I had to see Dr. Adelsheimer for an unusual condition involving tendons. He explained my issue thoroughly and what he could and couldn't do for me. I felt much better leaving the office (even though there wasn't much he could do), knowing what I needed to do moving forward. Provided answers when none of my other MD's were able to (or willing to). He took is time and was compassionate and thorough.read more
Marti Carlin
Marti Carlin
19:04 13 Jul 21
My experience with Dr. Sally and Regenexx was delightful even with the pain! The staff are all courteous and showed real concern for my well being, efficient and thoughtful! The Doctor explained his every move and showed concern for my comfort, now to wait for results!read more
Vicki Palmer
Vicki Palmer
12:04 15 May 21
Dr. Sally and his staff are outstanding! It takes a strong, committed group of caring individuals to deliver quality service and a positive patient experience every time. I drive 2 hours each way to the Regenexx office because they are that good and my quality of life is important to me. I highly recommend Dr. Sally and his amazing team!read more
Scott S.
Scott S.
00:17 19 Mar 21
You will not be disappointed.. Allow yourself to 'think outside of the box'. Today's medical advances offer so many more options that are less envasive..easier on your body and better for you!read more
Renata Pytlak
Renata Pytlak
17:23 18 Mar 21
I was full of anxiety about my procedure. Every nurse from sitting there waiting and the ones in the surgery room were so caring and comforting. Everyone was very professional. It's only been two days but my procedure has really helped me. I'm looking forward to a healthy and quality life now. Thank you all!read more
Normajean Simpson
Normajean Simpson
16:43 11 Mar 21
What an experience with Regenexx Pittsburgh!! After going through a total knee replacement/surgery/rehab, I was NOT going to do that again. After researching alternatives and talking to friends, I found Regenexx Pittsburgh! The staff and doctors were VERY informative, kind, and helpful. My procedures went so much better than I expected and my rehab was successful. I really can’t say enough good things about Regenexx Pittsburgh.....check them out!!!read more
Kathy Wolf
Kathy Wolf
19:19 09 Mar 21

Learn About Regenerative Medicine with Our Free Webinars

Regenexx Pittsburgh is committed to educating patients and the community on the benefits and advancements in non-surgical orthopedic treatments. Join our free webinars to gain valuable insights and empower your decision-making with knowledge straight from leading experts in regenerative medicine.

ipad with regenexx logo and hiker photo
LIVE & FREE DOCTOR-LED WEBINARS

Non-Surgical Orthopedics for Sports & Joint Pain Injuries

Presented by Dr. Paul Lieber
June 19, 2024 @ 7:00 pm

Free Pittsburgh Joint Pain Seminar

Non-Surgical Orthopedics for Sports Injuries & Joint Pain

Dr. Paul Lieber will lead the seminar and will answer questions about your condition live.
Thursday, October 26, 2023 @ 7:00 pm
Location: Monroeville Public Library (Program Room)
People attending Regenexx Seminar
ipad with regenexx logo and hiker photo

Free Doctor-Led Joint Pain Webinar

Upcoming Webinar: Non-Surgical Orthopedics for Pain Reduction and Improved Function

Don’t miss our upcoming live webinar, where Dr. Paul Lieber will discuss innovative non-surgical techniques to treat orthopedic conditions.

June 19, 2024, at 7:00 pm 

This session will cover how procedures like PRP therapy and stem cell treatments can dramatically reduce pain and enhance daily functionality without the risks associated with surgery. Register today to secure your spot and have your questions answered live!

Free Pittsburgh Joint Pain Seminar

On-Demand Webinar Series: Expert Insights into Regenerative Care

Explore our on-demand webinar series anytime, anywhere! These recorded sessions feature our team of specialists discussing various aspects of regenerative medicine, including detailed case studies and patient success stories.

Each webinar is designed to provide an in-depth look at how specific treatments are applied and the science behind their success. Gain access to these expert insights by signing up for our webinar series, and begin your journey towards a more informed health care choice.

People attending Regenexx Seminar
Free Pittsburgh Joint Pain Seminar

Non-Surgical Orthopedics for Sports Injuries & Joint Pain

Dr. Paul Lieber will lead the seminar and will answer questions about your condition live.
Thursday, October 26, 2023 @ 7:00 pm
Location: Monroeville Public Library (Program Room)
People attending Regenexx Seminar
ipad with regenexx logo and hiker photo
FREE Best-of Webinars-on-Demand

Non-Surgical Orthopedics for Sports & Joint Pain Injuries

One Best-Of 45-Minute-ish Webinar Each from Dr. Paul Lieber, Dr. Marc Adelsheimer and Dr. Jesse Sally
SAve Research Time with

Doctor FAQ Videos

Get access to multiple short doctor videos covering patient FAQs.
We will email you a link to a webpage you can access any time in the future.

Diagnosed with bone-on-bone knee pain? Is it really Sciatica? And many more

Insights and Updates from Regenexx Pittsburgh

Cutting-Edge Research and News in Regenerative Medicine

Regenexx Pittsburgh Patient Success Stories

Regenexx Pittsburgh:
Accessible Regenerative Care Across Multiple Locations

Main Clinic: Pittsburgh Location for Regenexx Treatments

107 Gamma Drive, Suite 220
Gamma Medical Center
Pittsburgh, PA 15238
412-963-6480

Serving McMurray, Bridgeville, and Washington with Expert Care

451 Valley Brook Road
Suite 201
McMurray 15317
412-963-6480

Are You a Candidate for Regenexx Treatments?

Take the Regenexx
Candidate Assessment

Schedule a Consultation
with Our Pittsburgh Specialists

Hand & Wrist

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Hand & Wrist Treatments >

Commonly Treated Conditions:

  • Hand Arthritis
  • Basal Joint Arthritis or CMC / Carpometacarpal
  • Arthritis
  • Instability
  • TFCC Tear
  • Carpal Tunnel SyndromeTrigger Finger

Shoulder

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Shoulder Treatments >

Commonly Treated Conditions:

  • Rotator cuff tears
  • Arthritis of the shoulder joint
  • Thoracic outlet syndrome
  • Labral tears or degeneration
  • Rotator cuff tendonitis & tendonosis
  • AC Joint Separation
  • Recurrent shoulder dislocations

Cervical Spine

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Spine Treatments >

Commonly Treated Conditions:

  • Cervical Instability
  • Cervical Facet Injury
  • Neck, Back or Rib Instability
  • Many More Disc and Cervical Issues Causing Pain

Lower Spine

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Spine Treatments >

Commonly Treated Conditions:

  • Lumbar Facet Injury
  • Degenerative Disc Disease
  • Herniated or Bulging Disc
  • Radiculopathy (pinched nerve)
  • SI Joint Syndrome
  • Many More Disc and Low Back Issues

Elbow

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Elbow Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Instability
  • Tennis Elbow or Golfer’s Elbow
  • Nerve entrapment (ulnar nerve)

Hip

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Hip Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Osteonecrosis
  • Bursitis
  • Tendinopathy
  • Labral / Labrum Tear

Knee

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Knee Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Meniscus Tears
  • Patellofemoral
  • Syndrome/Chondomalacia
  • ACL Tears + PCL, LCL & MCL Tears & Sprains
  • Patellar Tendonitis
  • Pes anersine bursitis
  • Baker’s cyst
  • Instability
  • Hamstrings Tendinopathy & Biceps Femoris Insertional Tendinopathy

Foot & Ankle

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Foot & Ankle Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Ankle Instability
  • Plantar fasciitis
  • Peroneal tendon tear or split
  • Ligament sprain or tear
  • Sub-talar arthritis or instability
  • Tarsal tunnel syndrome
  • Bunions

About Regenexx Pittsburgh COVID-19 Protection Zone

At Regenexx Pittsburgh, we are foremost committed to the health and safety of our patients. Our team adheres strictly to COVID-19 protection protocols and ALL staff wear masks and are COVID-19 vaccinated.

Advanced IOF Certifications

Certified at the highest level for Ankle / Foot, Wrist / Hand, Hip, Knee, Shoulder, and Spine Intradiscal

Specialized Certifications

Top available certifications in Diagnostic Ultrasound, Bone Marrow and Adipose Aspirate, and Nucleated Cell Counting

Educational Certifications

Our doctors have earned both General Instructor as well as Spine Instructor certifications.