Platelet-Rich Plasma (PRP) Treatments

Get back to doing what you love, without surgery

Regenexx® Pittsburgh is the Area's Only Regenexx Network Provider

Regenexx® Procedures provide non-surgical treatment options for those suffering from pain related to osteoarthritis, joint injuries, spine pain, overuse conditions, and common sports injuries. Regenexx procedures have helped thousands of patients improve their quality of life, return to the activities they enjoy, and avoid the need for surgery or joint replacement.

Regenexx® Physicans

A Highly Skilled, Selective Network

Regenexx Physicians represent a very selective, highly-skilled, interventional orthopedics network that is 100% focused on joint, tendon, ligament, spine, and bone conditions.

Extensive Training & Experience

Regenexx physicians are musculoskeletal experts with extensive training and experience in the diagnosis and treatment of musculoskeletal conditions, and complex, image-guided injections of your body’s own healing agents to treat orthopedic issues.

Research. Data.
Transparency.

Regenexx patient outcomes are tracked in a registry and with that information, we provide transparent outcome data for those who may be considering this treatment option. View outcome data.

Regenexx-SCP Procedures

Super Concentrated Platelet-Rich Plasma & Platelet Lysate Procedures

Platelet Rich Plasma (PRP) and Platelet Lysate are Platelet procedures that contain healing growth factors from your own blood that promote your body’s natural ability to repair itself. The use of PRP to treat joint, tendon, ligament, and muscle injuries is becoming well known, thanks to exposure from professional athletes. Platelet injections have a stimulating effect on the repair cells within the targeted area, making those cells work harder to perform their natural job of healing the body. Like all Regenexx procedures, Regenexx SCP procedures are performed with high-level imaging guidance to ensure the most accurate placements of cells into the desired area. Our Advanced Platelet Procedures are more concentrated and purer than PRP created by the automated machines used at most regenerative medicine clinics, increasing its ability to stimulate the body’s natural healing response. Platelet procedures are commonly used for soft tissue injuries, mild arthritis, spine conditions, and around nerves.

Considering a PRP Injection?
Checkout our FAQ.

PRP treatment has become a big deal this past decade. It’s being used by professional athletes and weekend warriors alike. So what is a PRP injection and does it work?

PRP stands for platelet-rich plasma, which is created by taking blood and concentrating the platelets in plasma. Why do this? The platelets in your blood are responsible for clotting. They also have growth factors in them which help stimulate repair of the damaged tissue.

What are growth factors? Think of growth factors like espresso shots for local repair cells. They stimulate other cells to do more work and can even call the needed repair cells to the area. In the platelet, they live in packets called alpha granules.

Why Regenexx PRP Mixtures are Better than Standard PRP / Platelet-Rich Plasma

In most clinics that offer PRP therapies, the method of developing PRP involves removing a patient’s blood and running it through a simple bedside centrifuge machine to separate the plasma and concentrate the blood platelets, which are then immediately extracted and used as the injectate. These devices are not great at getting rid of unfavorable cells from the resulting mixture. Our lab tests show that white and red blood cells have an inhibiting effect on the same stem cells the platelets are attempting to stimulate and might cause excessive inflammation following the injection.

Because of its concentration levels of platelets, Regenexx’s Super Concentrated PRP takes on an amber color. It has been shown to deliver up to 10 – 40x times more platelet concentrations than the standard “bloody” PRP.

Our PRP is purer, concentrated, and customizable because it is produced in a laboratory setting by an experienced technician who can separate and concentrate all the blood’s good components and remove the unfavorable ones.

Much of this depends on what’s being treated. While the effects on joints can be quick, tendon or ligament treatment often takes longer to show results. In these types of treatments, most patients take 2-4 months to improve.

You can watch Dr. Centeno, the founder of Regenexx, give a good explanation of PRP recovery times in this video:

PRP is not covered by most health insurance plans, other than the Regenexx PRP procedures that are covered by some employer-sponsored health plans.

The outcomes research on PRP is getting more and more clear by the day. Here are the areas where we have very good research:

  • Knee Arthritis – In a recent larger review of many different high-level studies, PRP was shown to be effective in treating knee arthritis. Some research shows that PRP tends to work better in patients with less severe arthritis, while another shows that the severity of arthritis makes no difference.
  • Tennis Elbow – PRP injection has also been shown to be more effective than steroid shots in the treatment of tennis elbow (lateral epicondylitis).
  • Spine – PRP works better than steroid shots for the treatment of sacroiliac (SI) pain. PRP also helps patients with low back pain caused by bad and painful discs. PRP has also been shown to be more effective than steroid injections for facet joint pain.
  • Achilles Tendinopathy – This one is a bit murkier, but the most recent research shows that PRP likely works for treating Achilles tendon pain. In addition, one study went so far as to take a small piece of the Achilles after injection treatment which showed better collagen structure in the PRP injected tendon than the one injected with placebo.

Other things PRP may be able to help include partial rotator cuff tears – (a small study has shown that PRP injection can help, but no high-level research has been done). Having said that, we routinely use high-dose LP-PRP to help these patients.

PRP is different from a stem cell injection.

Think of PRP as a stimulus for repair, sort of like an espresso shot for all of the local repair cells. Stem cells are like a general contractor for the repair job that can also turn into the brick and mortar needed. In general, we’ve found that PRP tends to work better for mild arthritis and partial ligament and tendon tears. However, bone marrow stem cells tend to be better at treating more severe arthritis and bigger tendon tears.

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What is PRP?

Your Guide to Platelet Rich Plasma Treatments

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About Regenexx Pittsburgh COVID-19 Protection Zone

At Regenexx Pittsburgh, we are foremost committed to the health and safety of our patients. Our team adheres strictly to COVID-19 protection protocols and ALL staff wear masks and are COVID-19 vaccinated.

Advanced IOF Certifications

Certified at the highest level for Ankle / Foot, Wrist / Hand, Hip, Knee, Shoulder, and Spine Intradiscal

Specialized Certifications

Top available certifications in Diagnostic Ultrasound, Bone Marrow and Adipose Aspirate, and Nucleated Cell Counting

Educational Certifications

Our doctors have earned both General Instructor as well as Spine Instructor certifications.

Knee

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Knee Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Meniscus Tears
  • Patellofemoral
  • Syndrome/Chondomalacia
  • ACL Tears + PCL, LCL & MCL Tears & Sprains
  • Patellar Tendonitis
  • Pes anersine bursitis
  • Baker’s cyst
  • Instability
  • Hamstrings Tendinopathy & Biceps Femoris Insertional Tendinopathy

Lower Spine

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Spine Treatments >

Commonly Treated Conditions:

  • Lumbar Facet Injury
  • Degenerative Disc Disease
  • Herniated or Bulging Disc
  • Radiculopathy (pinched nerve)
  • SI Joint Syndrome
  • Many More Disc and Low Back Issues

Foot & Ankle

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Foot & Ankle Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Ankle Instability
  • Plantar fasciitis
  • Peroneal tendon tear or split
  • Ligament sprain or tear
  • Sub-talar arthritis or instability
  • Tarsal tunnel syndrome
  • Bunions

Cervical Spine

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Spine Treatments >

Commonly Treated Conditions:

  • Cervical Instability
  • Cervical Facet Injury
  • Neck, Back or Rib Instability
  • Many More Disc and Cervical Issues Causing Pain

Shoulder

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Shoulder Treatments >

Commonly Treated Conditions:

  • Rotator cuff tears
  • Arthritis of the shoulder joint
  • Thoracic outlet syndrome
  • Labral tears or degeneration
  • Rotator cuff tendonitis & tendonosis
  • AC Joint Separation
  • Recurrent shoulder dislocations

Elbow

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Elbow Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Instability
  • Tennis Elbow or Golfer’s Elbow
  • Nerve entrapment (ulnar nerve)

Hip

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Hip Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Osteonecrosis
  • Bursitis
  • Tendinopathy
  • Labral / Labrum Tear

Hand & Wrist

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Hand & Wrist Treatments >

Commonly Treated Conditions:

  • Hand Arthritis
  • Basal Joint Arthritis or CMC / Carpometacarpal
  • Arthritis
  • Instability
  • TFCC Tear
  • Carpal Tunnel SyndromeTrigger Finger