Get back to doing what you love, without surgery
Regenexx Physicians represent a very selective, highly-skilled, interventional orthopedics network that is 100% focused on joint, tendon, ligament, spine, and bone conditions.
Regenexx physicians are musculoskeletal experts with extensive training and experience in the diagnosis and treatment of musculoskeletal conditions, and complex, image-guided injections of your body’s own healing agents to treat orthopedic issues.
PRP stands for platelet-rich plasma, which is created by taking blood and concentrating the platelets in plasma. Why do this? The platelets in your blood are responsible for clotting. They also have growth factors in them which help stimulate repair of the damaged tissue.
What are growth factors? Think of growth factors like espresso shots for local repair cells. They stimulate other cells to do more work and can even call the needed repair cells to the area. In the platelet, they live in packets called alpha granules.
In most clinics that offer PRP therapies, the method of developing PRP involves removing a patient’s blood and running it through a simple bedside centrifuge machine to separate the plasma and concentrate the blood platelets, which are then immediately extracted and used as the injectate. These devices are not great at getting rid of unfavorable cells from the resulting mixture. Our lab tests show that white and red blood cells have an inhibiting effect on the same stem cells the platelets are attempting to stimulate and might cause excessive inflammation following the injection.
Because of its concentration levels of platelets, Regenexx’s Super Concentrated PRP takes on an amber color. It has been shown to deliver up to 10 – 40x times more platelet concentrations than the standard “bloody” PRP.
Our PRP is purer, concentrated, and customizable because it is produced in a laboratory setting by an experienced technician who can separate and concentrate all the blood’s good components and remove the unfavorable ones.
Much of this depends on what’s being treated. While the effects on joints can be quick, tendon or ligament treatment often takes longer to show results. In these types of treatments, most patients take 2-4 months to improve.
You can watch Dr. Centeno, the founder of Regenexx, give a good explanation of PRP recovery times in this video:
PRP is not covered by most health insurance plans, other than the Regenexx PRP procedures that are covered by some employer-sponsored health plans.
The outcomes research on PRP is getting more and more clear by the day. Here are the areas where we have very good research:
Other things PRP may be able to help include partial rotator cuff tears – (a small study has shown that PRP injection can help, but no high-level research has been done). Having said that, we routinely use high-dose LP-PRP to help these patients.
Think of PRP as a stimulus for repair, sort of like an espresso shot for all of the local repair cells. Stem cells are like a general contractor for the repair job that can also turn into the brick and mortar needed. In general, we’ve found that PRP tends to work better for mild arthritis and partial ligament and tendon tears. However, bone marrow stem cells tend to be better at treating more severe arthritis and bigger tendon tears.
At Regenexx Pittsburgh, we are foremost committed to the health and safety of our patients. Our team adheres strictly to COVID-19 protection protocols and ALL staff wear masks and are COVID-19 vaccinated.