Avascular Necrosis Treatment in Pittsburgh – Avoid Hip Replacement with Advanced Orthobiologics

When the blood supply to your hip bone slows or stops, the result is something called avascular necrosis (AVN)—also known as osteonecrosis. Over time, the femoral head (top of the thigh bone) begins to weaken, collapse, and deteriorate. The pain can be deep and relentless, and if left untreated, often ends in a total hip replacement. At Regenexx Pittsburgh, we offer advanced, non-surgical orthobiologic treatments that may help slow or reverse the progression of AVN. Using your body’s own healing cells—concentrated and precisely guided into the damaged area—we aim to preserve your joint, reduce pain, and help you stay active without going under the knife.

What Is Avascular Necrosis of the Hip?

Avascular necrosis (AVN) is a condition where reduced blood flow to the femoral head leads to bone tissue death. As the bone loses strength, it can collapse—causing the joint to deteriorate and leading to significant pain and disability. AVN typically progresses through stages, from early cellular damage to full joint collapse.
 It often affects adults between 30 and 60 years old and may be triggered by trauma, medication use, or underlying health conditions.
 If caught early, there’s a window to intervene before permanent damage occurs.

Common Causes 
& Risk Factors

Symptoms of Avascular Necrosis

Pain-Related Symptoms

Mobility-Related Symptoms

Conventional Treatments 
& Limitations

Treatment Pros Cons
NSAIDs / Pain Meds
Easy to access; 
reduce symptoms
Don’t slow AVN progression; long-term use risks
Core Decompression Surgery
May improve blood flow 
in early cases
Invasive; unpredictable 
long-term benefit
Hip Replacement Surgery
Restores function in 
end-stage AVN
Major surgery; long rehab; limited implant lifespan
Watch-and-Wait Approach
Delays surgery
Often results in worsening and permanent damage

The Regenexx Approach: PRP & Bone Marrow Concentrate (BMC)

We don’t guess. We guide.

At Regenexx Pittsburgh, every procedure is customized to your condition and performed using advanced imaging for precision.

01

Platelet-Rich Plasma (PRP)

Ideal for early-stage AVN, PRP uses concentrated platelets from your blood to promote tissue repair and improve blood flow to the bone.

02

Bone Marrow Concentrate (BMC)

For moderate to advanced AVN (before collapse), BMC contains stem cells and powerful growth factors to support bone regeneration.

We help you choose the right protocol based on your AVN stage and imaging.

What to Expect from Treatment

Comprehensive Consultation
Your Regenexx physician will review your imaging, examine your hip, and walk you through your options.
On the day of your injection, your blood or bone marrow is collected, processed, and reinjected—no hospital stay required.
Most patients resume light activity in a few days. Strenuous movement is limited for 3–6 weeks, depending on your case.
Many patients notice improvement within 6–12 weeks, with continued healing for months afterward.

Are You a Candidate?

You may be a good fit for Regenexx treatment if:

Why Patients Choose 
Regenexx Pittsburgh

Over 115,000 Regenexx procedures performed nationwide

Board-certified physicians 
with orthopedic expertise

Treatments backed by published data and a clinical outcomes registry

Real-time, image-guided 
injections for accuracy

Real-time, image-guided 
injections for accuracy

Personalized care—no 
cookie-cutter protocols

What Patients Are Saying

At 42, I was told a hip replacement was my only option. Regenexx gave me a second chance. After BMC therapy, my pain is down and I’m back to hiking with my family.

— Jason, Wexford

My AVN was early-stage, and I caught it just in time. PRP was a game-changer—I avoided surgery, and I feel like myself again.

— Melissa, South Hills

Frequently Asked Questions

How long do results last?
Many patients experience long-term improvement, especially when treated in early stages.
Orthobiologic treatments may slow or reverse AVN progression. Complete reversal isn’t guaranteed, but many avoid or delay surgery.
You may feel pressure or soreness, but procedures are done under local anesthesia and well-tolerated.
Side effects are typically mild—like soreness or bruising. Serious risks are rare in our hands.
These treatments are not usually covered, but we offer payment plans and can walk you through options.

Start Healing Without Surgery

Avascular necrosis doesn’t have to be a countdown to joint replacement. With Regenexx Pittsburgh, you may have a chance to preserve your natural hip and keep doing what you love—without hospitals, downtime, or unnecessary interventions.

About Regenexx Pittsburgh COVID-19 Protection Zone

At Regenexx Pittsburgh, we are foremost committed to the health and safety of our patients. Our team adheres strictly to COVID-19 protection protocols and ALL staff wear masks and are COVID-19 vaccinated.

Advanced IOF Certifications

Certified at the highest level for Ankle / Foot, Wrist / Hand, Hip, Knee, Shoulder, and Spine Intradiscal

Specialized Certifications

Top available certifications in Diagnostic Ultrasound, Bone Marrow and Adipose Aspirate, and Nucleated Cell Counting

Educational Certifications

Our doctors have earned both General Instructor as well as Spine Instructor certifications.

Knee

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Knee Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Meniscus Tears
  • Patellofemoral
  • Syndrome/Chondomalacia
  • ACL Tears + PCL, LCL & MCL Tears & Sprains
  • Patellar Tendonitis
  • Pes anersine bursitis
  • Baker’s cyst
  • Instability
  • Hamstrings Tendinopathy & Biceps Femoris Insertional Tendinopathy

Lower Spine

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Spine Treatments >

Commonly Treated Conditions:

  • Lumbar Facet Injury
  • Degenerative Disc Disease
  • Herniated or Bulging Disc
  • Radiculopathy (pinched nerve)
  • SI Joint Syndrome
  • Many More Disc and Low Back Issues

Foot & Ankle

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Foot & Ankle Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Ankle Instability
  • Plantar fasciitis
  • Peroneal tendon tear or split
  • Ligament sprain or tear
  • Sub-talar arthritis or instability
  • Tarsal tunnel syndrome
  • Bunions

Cervical Spine

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Spine Treatments >

Commonly Treated Conditions:

  • Cervical Instability
  • Cervical Facet Injury
  • Neck, Back or Rib Instability
  • Many More Disc and Cervical Issues Causing Pain

Shoulder

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Shoulder Treatments >

Commonly Treated Conditions:

  • Rotator cuff tears
  • Arthritis of the shoulder joint
  • Thoracic outlet syndrome
  • Labral tears or degeneration
  • Rotator cuff tendonitis & tendonosis
  • AC Joint Separation
  • Recurrent shoulder dislocations

Hip

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Hip Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Osteonecrosis
  • Bursitis
  • Tendinopathy
  • Labral / Labrum Tear

Elbow

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions. View Details About Elbow Treatments >

Commonly Treated Conditions:

  • Arthritis
  • Instability
  • Tennis Elbow or Golfer’s Elbow
  • Nerve entrapment (ulnar nerve)

Hand & Wrist

Regenexx® Procedures are non-surgical injection treatments that are intended to help reduce pain and improve function for those who are suffering from pain due to common injuries, arthritis, and overuse conditions.

View Details About Hand & Wrist Treatments >

Commonly Treated Conditions:

  • Hand Arthritis
  • Basal Joint Arthritis or CMC / Carpometacarpal
  • Arthritis
  • Instability
  • TFCC Tear
  • Carpal Tunnel SyndromeTrigger Finger