Non-Surgical Knee Pain Relief in Pittsburgh – Regenexx ® Procedures
Avoid invasive surgery. Regenexx® Pittsburgh offers advanced, image-guided injections using your body’s own repair cells to help reduce knee pain and improve mobility.
Why Regenexx May Be a Better First Step Than Surgery
Many knee injuries and chronic conditions don’t require immediate surgery. Regenexx Pittsburgh offers precise, non-surgical procedures performed by a musculoskeletal expert — often with minimal downtime and faster recovery compared to traditional options.
Uses Your Body’s Own Repair Cells — Bone Marrow Concentrate or PRP
Performed by a Regenexx-Certified Orthopedic Physician
Convenient Pittsburgh Locations
Treatments Tailored to Your Imaging & Diagnosis
Outcomes Tracked in a National Registry of Over 40,000 Procedures
Conditions We Commonly
Treat with Regenexx
Regenexx Pittsburgh evaluates and treats a wide range of orthopedic knee conditions for patients throughout Fox Chapel, Aspinwall, Highland Park, and nearby areas.
Knee Osteoarthritis
Degeneration of cartilage causing joint stiffness and pain — common in aging adults.
Meniscus Tears
Tears from wear or trauma that limit motion and may lead to unnecessary surgical removal.
ACL, MCL, PCL, LCL Injuries
Partial ligament sprains and non-retracted tears are evaluated for non-surgical options.
Patellar Tendonitis (Jumper’s Knee)
Inflammation or strain of the tendon connecting kneecap to shinbone.
Bursitis & Baker's Cysts
Fluid-filled sacs behind the knee caused by inflammation or stress.
Chronic Instability or Overuse Injuries
Instability and flare-ups due to old injuries or high-impact activity.
Not sure if your condition qualifies?
How Regenexx KNEE Procedures Work
Regenexx uses your body’s own components — either blood or bone marrow — to support tissue repair. All procedures are performed under precise image guidance to target the affected area and avoid surrounding structures.
FDA Disclaimer:
Regenexx procedures comply with FDA regulations for autologous use and minimal manipulation but are not FDA-approved drugs or devices. All procedures are physician-directed and performed under medical supervision.
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REGENEXX-SD – BONE MARROW CONCENTRATE
Collected from the back of the hip, processed to concentrate healing cells, and re-injected into the knee. Commonly used for arthritis, ligament injuries, and moderate-to-severe cases.
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REGENEXX-SCP – ADVANCED PLATELET PROCEDURES (PRP)
Drawn from your blood and processed to create high-purity, high-concentration platelet-rich plasma. Often used for early arthritis, overuse injuries, or tendon issues.
Are Regenexx Knee Procedures Safe?
Risks & Safety Considerations: Regenexx procedures are minimally invasive, but like any medical procedure, they carry potential risks. These may include:
What Results Are
Patients Reporting?
Based on data from the Regenexx national patient registry for knee procedures (3,585 patients as of March 2021):
Knee Function Improvement
Patients improved from an average of 55% function to 74% at one month (FRI scale)
Knee Pain Reduction
Average pain decreased from 4.2/10 to 2.3/10 at one month (NPS scale)
Overall Knee Perception
Patients rated their knees 37% better on average after one month (SANE scale)
Individual results may vary. For more details, visit Regenexx Outcome Data.
What Is Knee Recovery Like?
Most patients return to light activity within 1–3 days. Your recovery plan may include:
Week 1
Walking & gentle range of motion
Week 2–3
Gradual reintroduction of strengthening
Week 4–6+
Progressive return to activity
You’ll receive a customized recovery plan from your Regenexx physician.
Frequently Asked Questions
How do I know if I’m a candidate for Regenexx?
The best way to find out is by completing our brief Candidate Form. Our medical team will review your information and imaging (if available) to determine if one of our procedures may be appropriate for your condition.
What types of knee issues do you treat?
We commonly evaluate patients with arthritis, meniscus tears, ACL or MCL injuries, patellar tendinitis, and other orthopedic conditions. However, your eligibility depends on a number of factors, so a personal evaluation is key.
Are Regenexx procedures covered by insurance?
Platelet-rich plasma (PRP) is derived from your blood and is commonly used for milder injuries or early arthritis. Bone marrow concentrate is collected from your hip and may be recommended for more advanced or complex conditions. Your physician will guide you on the best approach based on your needs.
What’s the difference between PRP and bone marrow concentrate?
Regenexx uses bone marrow concentrate, which contains a variety of cells — including stem cells — that are naturally present in your body. These cells are not manipulated or expanded in a lab, and the procedure complies with current FDA guidelines.
Is this a stem cell procedure?
Regenexx uses bone marrow concentrate, which contains a variety of cells — including stem cells — that are naturally present in your body. These cells are not manipulated or expanded in a lab, and the procedure complies with current FDA guidelines.
How long does the procedure take?
Most Regenexx procedures are completed in about 60 to 90 minutes, depending on the treatment plan. You’ll be able to go home the same day.
What is recovery like after the procedure?
Most patients experience minimal downtime. You may feel some soreness in the treated area for a few days, and activity restrictions vary based on the type of procedure. We’ll give you a customized post-care plan.
Are there risks or side effects?
As with any medical procedure, there are potential risks, including bleeding, soreness, or infection. However, Regenexx procedures are minimally invasive and have a lower risk profile compared to surgical alternatives.
Still have questions?
Free Resources to Help You Decide
Report: 10 Rarely Discussed Facts About Knee Replacement Surgery
Includes Medicare data, complication rates, and lesser-known risks of common surgical options.
Guide: Understanding Regenexx Knee Procedures
- How each procedure works
- What conditions qualify
- Recovery expectations
- Questions to ask your provider
We’ll never spam you or sell your information.
Meet the Physician Behind Regenexx Pittsburgh
At Regenexx Pittsburgh, all procedures are performed by a board-certified physician — not a technician or assistant. From your initial consultation to your procedure and follow-up, your care is guided by a doctor with deep experience in musculoskeletal medicine and regenerative orthopedic therapies.
Dr. Jesse A. Sally
Sports medicine specialist helping Pittsburgh patients recover without surgery.
Dr. Paul S. Lieber
Non-surgical spine and musculoskeletal expert focused on long-term pain relief
Dr. Marc Adelsheimer
Pioneer in regenerative rehab with a track record of functional recovery in Pittsburgh patients.
Where to Find
Regenexx Pittsburgh
Directions & Landmarks:
Located just off Route 28 near Fox Chapel Plaza. Free parking onsite. Easy access from Highland Park, Aspinwall, and O’Hara Township.
Glossary of Terms
| Term | Definition |
|---|---|
|
Autologous |
Originating from your own body (e.g., blood or marrow) |
|
PRP |
Platelet-Rich Plasma — plasma with concentrated platelets that support healing |
|
BMC |
Bone Marrow Concentrate — marrow cells processed to concentrate healing components |
|
Image-Guided Injection |
Use of ultrasound or fluoroscopy to guide precise needle placement |
