Non-Surgical Relief for Knee Osteoarthritis in Pittsburgh
Regenexx PRP & BMC Injections for Long-Term Joint Function—Without Surgery
What Is Knee Osteoarthritis?
Knee osteoarthritis (OA) is a degenerative joint condition where the cartilage that cushions your knee gradually wears down. As the cartilage thins, bones begin to rub against each other—causing pain, stiffness, swelling, and loss of mobility. You might notice:
Pain that worsens with activity or after long periods of rest
Swelling around the knee joint
Cracking or grinding sounds when moving your knee
Decreased range of motion or instability
OA is often labeled “wear and tear,” but there’s more to it than just aging. Injury history, inflammation, biomechanics, and even weight can all accelerate joint breakdown.
A Smarter Approach to Knee Arthritis Treatment
Regenexx Pittsburgh offers an alternative to temporary fixes or invasive surgery. Our treatments focus on stimulating your body’s natural healing processes—reducing inflammation and supporting tissue repair. We offer:
- PRP Injections (platelet-rich plasma)
- BMC Injections (bone marrow concentrate—commonly referred to as “stem cell therapy”)
Each treatment plan is customized based on your condition, imaging, and goals. All procedures are performed by board-certified physicians using precise imaging guidance for accuracy and effectiveness. Regenexx procedures are backed by one of the largest databases of regenerative orthopedic outcomes in the world.
How PRP and BMC Work
Platelet-Rich Plasma (PRP) delivers a concentrated dose of your body’s own healing growth factors directly to the affected joint. This can help reduce inflammation and encourage repair of damaged tissue. Bone Marrow Concentrate (BMC) includes additional signaling cells collected from your bone marrow. These cells support tissue healing and may be more appropriate for more advanced degeneration. Unlike cortisone or hyaluronic acid injections, these procedures don’t just mask symptoms—they aim to improve joint health and function over time. All Regenexx procedures are:
- Precisely delivered using fluoroscopy or ultrasound
- Performed in-office with minimal downtime
- Developed and refined through ongoing clinical research
Are You a Candidate?
You may be a good candidate for Regenexx if:
- You’ve been diagnosed with mild to moderate knee osteoarthritis
- You want to avoid or delay knee replacement surgery
- You’ve tried cortisone, gel injections, or physical therapy with limited results
- You’re looking for a more natural solution focused on healing
We also treat some severe cases if there’s still joint space and mobility remaining. An in-person evaluation will help determine the best path forward.
Real Patients. Real Stories.
Before Regenexx, my knees hurt climbing the stairs in my South Hills home. Now I’m walking miles a day without pain.
— Pittsburgh Patient, Age 63
I was told I needed a knee replacement. PRP at Regenexx gave me my golf swing back—and more time before surgery.
— Pittsburgh Patient, Age 57
What to Expect: From Evaluation to Recovery
Evaluation & Imaging
Evaluation & Imaging
Custom Treatment Plan
Custom Treatment Plan
Procedure Day
Procedure Day
Recovery
Recovery 
Are There Any Risks or Downsides?
While regenerative treatments are generally safe and well-tolerated, every procedure has risks. The most common side effects include:
- Temporary soreness or swelling at the injection site
- No guaranteed results
- Not appropriate for all stages of OA or all patients
Our team will walk you through all options—including PT, bracing, weight management, and when appropriate, surgery.
Regenexx vs. Traditional Treatments
| Treatment | Goal | Typical Duration | Pros | Cons |
|---|---|---|---|---|
|
Regenexx PRP/BMC |
Stimulate healing |
Varies |
Minimally invasive, targeted, customized |
Not covered by most insurance |
|
Cortisone Injection |
Reduce inflammation |
Weeks |
Fast pain relief |
May accelerate cartilage damage |
|
Hyaluronic Acid (Gel Shots) |
Lubricate joint |
Weeks–months |
Widely used |
Short-term relief, inconsistent results |
|
Knee Replacement |
Replace damaged joint |
Years (post-surgery) |
Long-term fix for end-stage OA |
Major surgery, long recovery, possible complications |
Take the First Step Toward Relief
Don’t wait until knee pain takes over your life. If you’re looking for a safe, effective alternative to surgery—right here in Pittsburgh—schedule a Regenexx evaluation today. Conveniently located near downtown Pittsburgh, with easy access from Wexford, Cranberry, Mt. Lebanon, and surrounding neighborhoods.
Call Our Office
(412) 963-6480
Frequently Asked Questions
How long does PRP last for knee osteoarthritis?
Is Regenexx covered by insurance?
Some insurance may cover evaluation or imaging. PRP and BMC are typically not covered.
